Ets binding sites: Difference between revisions
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(New page: * FGF activates the Ets-protein by dephosphorylation * Ets then binds and activates heart-specific genes * Ets binding sites: ** GGAA (Elf3 on uniprobe http://the_brain.bwh.harvard.edu/un...) |
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##Plot with Ets-motifs in them: | ##Plot with Ets-motifs in them: | ||
###Add to genome browser | ###Add to genome browser | ||
#### Funny: lrr2 and lrr3 not found in ci2 | |||
###Extract alignments | ###Extract alignments | ||
###Get conserved motifs | ###Get conserved motifs | ||
Latest revision as of 19:53, 4 May 2010
- FGF activates the Ets-protein by dephosphorylation
- Ets then binds and activates heart-specific genes
- Ets binding sites:
- GGAA (Elf3 on uniprobe http://the_brain.bwh.harvard.edu/uniprobe/details2?id=90)
- Commonly GGA(TA)
- Steps:
- Available enhancers
- Plot with Ets-motifs in them:
- Add to genome browser
- Funny: lrr2 and lrr3 not found in ci2
- Extract alignments
- Get conserved motifs
- Get non-conserved motifs
- Plot with RSAT
- Add to genome browser
- Over-rep motifs
- get background: all conserved blocks around non-microarray genes
- Use deme or meme?
- Plot with Ets-motifs in them:
