Ets binding sites

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Revision as of 19:51, 4 May 2010 by Max (talk | contribs) (New page: * FGF activates the Ets-protein by dephosphorylation * Ets then binds and activates heart-specific genes * Ets binding sites: ** GGAA (Elf3 on uniprobe http://the_brain.bwh.harvard.edu/un...)
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  • FGF activates the Ets-protein by dephosphorylation
  • Ets then binds and activates heart-specific genes
  • Steps:
  1. Available enhancers
    1. Plot with Ets-motifs in them:
      1. Add to genome browser
      2. Extract alignments
      3. Get conserved motifs
      4. Get non-conserved motifs
      5. Plot with RSAT
    2. Over-rep motifs
      1. get background: all conserved blocks around non-microarray genes
      2. Use deme or meme?
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