User:Turelli

Professional address: EPFL, SV-LVG AI 3 351, Station 19, 1015 Lausanne, Switzerland Tel: +41/21.693.18.11, Fax: +41/21.693.16.97 E-mail: priscilla.turelli@epfl.ch

______________________________________________________ Positions

2005-now: Research associate in Pr D. Trono’s laboratory, Federal School of Life Sciences, Laboratory of Virology and Genetics, Switzerland 2001-2004: Senior post-doctoral research fellow in Pr D. Trono’s laboratory, Department of Microbiology, Geneva School of Medicine, Switzerland 1997-2001: Post-doctoral research fellow in Pr D. Trono’s laboratory, Department of Microbiology, Geneva School of Medicine, Switzerland

____________________________________________________Honors and fellowships

2004: Bristol-Myers Squibb AIDS AWARD 1997-1999: Human Frontier Science Program fellowship

__________________________________________________ Education

June 1997: PhD in cellular biology. Final mark: “very good with jury congratulations”. Université de la Méditerranée, France.

June 1993: Post-graduate diploma in cellular biology and microbiology. INSERM U372, Marseille-Luminy, université de Provence, France.

June 1992: Master in cellular biology – Specialty: genetic. Final mark: “good”. Best master student of this year. Université de la Méditerranée, France.

June 1987: Scientific baccalaureate, France.

___________________________________________ Teaching experience

2005-now: supervising of phD students and technicians in Pr. D. Trono’s laboratory. 2002: Tutor in virology for medical students, 2nd year, Geneva School of Medicine, Switzerland.

1996-1997: Tutor in molecular biology and biochemistry for under-graduate students, Université de la Méditerranée, Aix Marseille II, France.

___________________________________________ Miscellaneous

Languages: French (native language), English (written and spoken), German (basic) Activities: Classic and modern dance (17 years of practice) Good knowledge of Africa (8 years living in Gabon)

______________________________________ Publications

Bulliard Y, Turelli P, Röhrig UF, Zoete V, Mangeat B, Michielin O, Trono D. Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition. J Virol., Dec;83(23):12611-21. Epub 2009 Sep 23 (2009).

Turelli P, Liagre-Quazzola A, Mangeat B, Verp S, Jost S, Trono D. APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice. J Virol., Jul;82(13):6585-90. Epub 2008 Apr 23 (2008).

Maillard PV, Reynard S, Serhan F, Turelli P, Trono D. Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha. PLoS Pathog., Dec 28;3(12):e200 (2007).

Jost S, Turelli P, Mangeat B, Protzer U, Trono D. Induction of antiviral cytidine deaminases does not explain the inhibition of hepatitis B virus replication by interferons. J Virol., Oct;81(19):10588-96. Epub 2007 Jul 25 (2007).

Ariumi Y, Serhan F, Turelli P, Telenti A, Trono D The integrase interactor 1 (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription. Retrovirology, Aug 5;3:47 (2006).

P. Turelli and D. Trono. Editing at the crossroad of innate and adaptive immunity. Science, Feb 18, 307(5712):1061-5 (2005).

P. Turelli, S. Jost, B. Mangeat and D. Trono. Response to Comment on "Inhibition of Hepatitis B Virus Replication by APOBEC3G" Science, Sep 3, 305(5689):1403B (2004).

P. Turelli, S. Vianin and D. Trono. The innate antiretroviral factor APOBEC3G does not affect human LINE-1 retrotransposition in a cell culture assay. J. Biol. Chem., Oct 15;279(42):43371-3. Epub 2004 Aug 18. (2004).

P. Turelli, B. Mangeat, S. Jost, S. Vianin and D. Trono. Inhibition of Hepatitis B virus replication by APOBEC3G. Science, Mar 19, 303(5665):1829 (2004).

B. Mangeat, P. Turelli, S. Liao and D. Trono. A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action. J. Biol. Chem., Apr 9, 279(15):14481-3 Epub 2004 Feb 13 (2004).

B. Mangeat, P. Turelli, G. Caron, M. Friedli, L. Perrin and D. Trono. Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature, Jul 3, 424(6944):99-103 Epub 2003 May 28 (2003).

M. Guyader, E. Kiyokawa, L. Abrami, P. Turelli and D. Trono. Role for human immunodeficiency virus type 1 membrane cholesterol in viral internalization. J.Virol., Oct, 76(20):10356-64 (2002).

M. Berton, P. Turelli, D. Trono, C. Stein, E. Allémann and R. Gurny. Inhibition of HIV-1 in cell culture by oligonucleotide-loaded nanoparticles. Pharm. Res., Aug, 18(8):1096-101 (2001).

P. Turelli, V. Doucas, E. Craig, B. Mangeat, N. Klages, R. Evans, G. Kalpana, and D. Trono. Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: interference with early steps of viral replication. Mol. Cell., Jun, 7(6):1245-54 (2001).

G. Petursson, P. Turelli, S. Matthiasdottir, G. Georgsson, O.S. Andresson, S. Torsteinsdottir, R. Vigne, V. Andresdottir, E. Gunnarsson, G. Agnarsdottir and G. Quérat. Visna virus dUTPase is dispensable for neuropathogenicity. J.Virol., Feb, 72(2):1657-1661 (1998).

P. Turelli, F. Guigen, J.F. Mornex, R. Vigne and G. Quérat. dUTPase minus caprine arthritis-encephalitis virus is attenuated for pathogenesis and accumulates G to A substitutions.

J.Virol., Jun, 71(6):4522-4530 (1997).

P. Turelli, G. Petursson, F. Guigen, J. F. Mornex, R. Vigne and G. Quérat. Replication properties of dUTPase deficient mutants of caprine and ovine lentiviruses.

J.Virol., Feb, 70(2): 1213-1217 (1996).